Intermittent fasting (intermittent energy restriction or intermittent calorie restriction) is an umbrella term for various eating diet plans that cycle between a period of fasting and non-fasting over a defined period. Intermittent fasting is under preliminary research to assess if it can produce weight loss comparable to long-term calorie restriction.[1][2][3][4][5]


Finally, note that fasting to induce ketosis can also trigger a set of symptoms often known as the “keto flu.” Fasting ketosis symptoms may include decreased energy levels, increased cravings, digestive issues, muscle aches and dizziness. These symptoms can last between a few days to a few weeks when starting the ketogenic diet, but they typically subside once your body enters ketosis and begins to adapt.

Intermittent fasting (intermittent energy restriction or intermittent calorie restriction) is an umbrella term for various eating diet plans that cycle between a period of fasting and non-fasting over a defined period. Intermittent fasting is under preliminary research to assess if it can produce weight loss comparable to long-term calorie restriction.[1][2][3][4][5]


Every study seems to support cognitive and health benefits for IF. Studies are coming out showing it may help stave off heart disease and it’s even been shown to halt or possibly reverse brain-related diseases such as Alzheimer’s. If in doubt, check out Jason Fung’s youtube videos along with a couple of youtube researchers who do wonderful analytics, an American who lives in Japan who goes by, “Things I’ve Learned” and Thomas DeLauer’s IF material. I’ve been doing IF myself for a few months now and I feel better, more energy, better sleep, and controlled weight.
It requires less time (and potentially less money). Rather than having to prepare or purchase three to six meals a day, you only need to prepare two meals. Instead of stopping what you’re doing six times a day to eat, you simply only have to stop to eat twice. Rather than having to do the dishes six times, you only have to do them twice. Rather than having to purchase six meals a day, you only need to purchase two.
Both the keto diet and intermittent fasting trigger something referred to as autophagy. The latter is simply the technical term for a natural bodily function called “self-eating.” Although at first this may sound a bit frightening, autophagy is merely your body’s normal detoxification process, during which it eliminates contaminants and replaces them with newly formed, healthy cells.
While some nutrition experts contend that IF only works because it helps people naturally limit food intake, others disagree. They believe that intermittent fasting results are better than typical meal schedules with the same amount of calories and other nutrients. Studies have even suggested that abstaining from food for several hours a day does more than just limit the amount of calories you consume.

Surprisingly, since I've started intermittent fasting I've increased muscle mass (up 10 pounds from 205 to 215), decreased body fat (down 3% from 14% to 11%), increased explosiveness (set a personal best with a clean and jerk of 253 pounds a few months back), and decreased the amount of time I've spent training (down from 7.5 hours per week to 2.5 hours per week).

Fast for 16 hours of the day, and allow yourself a single eight-hour window for eating. This may be a good option for most beginners, because it represents the most subtle change from the standard three-meals-per-day lifestyle. As approximately eight of those fasting hours should be spent getting a good night’s sleep, that leaves only eight hours where participants need to be consciously avoiding food. For many, allowing themselves to eat normally from noon until 8pm gives them a stable meal schedule while also staying in a fasted state for the majority of the time.
Intermittent fasting is a technique that involves restricting your food intake to a certain time window each day and then fasting for a specific period. There are several different fasting methods, with many variations that can fit nearly any personal preference or routine. A few of the most common types of intermittent fasting include alternate day fasting, 16/8 fasting and the 5:2 diet, each of which varies based on the amount of time you spend fasting during the week.
You are probably wondering how there could possibly be a benefit to eating less frequently that goes beyond what you are already getting with a ketogenic diet. Restricting carbs and eating enough fat and protein does come with a plethora of health benefits, but when you add intermittent fasting to your lifestyle you can increase energy and reverse aging by harnessing the power of a nobel prize winning process.
So how long does it take to go into ketosis when fasting? On a standard keto diet, it typically takes around 2–3 days to reach ketosis, although it can take up to seven days in some cases. However, many people find that keto adaptation intermittent fasting can speed up the process and help your body burn through glycogen stores more quickly to help enter ketosis.
According to a study published in Translational Research in 2014, intermittent fasting can reduce your weight by 3 to 8 percent over three to 24 weeks. A systematic review published in Molecular and Cellular Endocrinology in 2015 confirmed these results by reporting that, on average, participants following a fasting diet lost between 7 and 11 pounds in 10 weeks.
The 5:2 diet, also known as the “Fast Diet,” involves restricting calories two days a week to 500 calories per day (with two 250 calorie meals), while eating normally for the other five days. For example, you might eat all of your regular meals Saturday through Wednesday, and eat 500 calories per day on Thursdays and Fridays.There isn’t a ton of research to back up this diet, although it was publicized by Michael Mosley, a British journalist and doctor. Since it doesn’t completely restrict food on the fasting days, it may also be an effective way to ease into fasting without shocking your system. The Fast Diet is considered safe for men and women.
As with Kinobody, the owner of Kinobody Greg O’Gallagher recommends you use coffee as a tool while helping you lose weight. Using coffee, to be more specific, black and only black coffee. Black as a skillet, coffee. No added sugar, creamer, sweeteners, or bulletproof coffee (that contain a mixture of stuff, mostly fats). Just ground up java bean and water heated until hot. I would also interject and recommend filtered water, or as I like to say, “use a filter or be the filter.” Who knows what lurks in the water we drink, and for that reason, let’s be cautious and use a filter.
While these five methods are the most well-known in terms of integrating periods of fasting into your eating schedule, there are many other similar philosophies based on meal timing. For those who prefer a more fluid, less rigid method, there’s also the concept of eating intuitively. Primal Diet proponent Mark Sisson is a supporter of the Eat WHEN (When Hunger Ensues Naturally) method, where dieters simply eat whenever their bodies ask them to. However, some believe this can also lead to overeating or overconsumption of calories, since our bodies’ hunger-induced choices may be more caloric than otherwise.
For this reason, certain experts believe that intermittent fasting improves a broad range of neuro-degenerative conditions, including stroke, Huntington’s disease, Parkinson’s disease, and Alzheimer’s disease. After conducting a study on animals, researchers at the National Institute on Aging, found that cyclical fasting helps neurons in the brain to resist degeneration and dysfunction.
This is probably a good time to mention that while I have practiced intermittent fasting consistently for the last year, I'm not fanatical about my diet. I work on building healthy habits that guide my behavior 90% of the time, so that I can do whatever I feel like during the other 10%. If I come over to your house to watch the football game and we order pizza at 11pm, guess what? I don't care that it's outside my feeding period, I'm eating it.

Articles and information on this website may only be copied, reprinted, or redistributed with written permission (but please ask, we like to give written permission!) The purpose of this Blog is to encourage the free exchange of ideas. The entire contents of this website is based upon the opinions of Dave Asprey, unless otherwise noted. Individual articles are based upon the opinions of the respective authors, who may retain copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the personal research and experience of Dave Asprey and the community. We will attempt to keep all objectionable messages off this site; however, it is impossible to review all messages immediately. All messages expressed on The Bulletproof Forum or the Blog, including comments posted to Blog entries, represent the views of the author exclusively and we are not responsible for the content of any message.
Amy Shah, MD, is double board-certified doctor who received her medical training from Cornell, Harvard and Columbia Universities. She has a thriving medical practice in the Phoenix area, where she sees more than 5,000 patients each year. In 2015, Dr. Shah was named one of the “Top 100 Women in Wellness to Watch” by MindBodyGreen and was a guest on the Dr. Oz show.
So here’s the deal. There is some good scientific evidence suggesting that circadian rhythm fasting, when combined with a healthy diet and lifestyle, can be a particularly effective approach to weight loss, especially for people at risk for diabetes. (However, people with advanced diabetes or who are on medications for diabetes, people with a history of eating disorders like anorexia and bulimia, and pregnant or breastfeeding women should not attempt intermittent fasting unless under the close supervision of a physician who can monitor them.)
Surprisingly, since I've started intermittent fasting I've increased muscle mass (up 10 pounds from 205 to 215), decreased body fat (down 3% from 14% to 11%), increased explosiveness (set a personal best with a clean and jerk of 253 pounds a few months back), and decreased the amount of time I've spent training (down from 7.5 hours per week to 2.5 hours per week).
Although there's no specific dietary recommendation when intermittent fasting, many people choose to combine it with a low-carb, ketogenic diet. When it's time to eat, include foods that are high in good fats and low in carbohydrates. That means eating nuts, seeds, vegetables, avocado, olives, meat and fish, while avoiding whole grains, fruits, starchy vegetables, sugary drinks and anything processed.
As a functional medicine practitioner, I see a wide range of health problems that all stem from chronic inflammation. And while acute inflammation is a natural and healthy response to help fight off pathogenic bacteria and infections, long-term chronic inflammation that doesn’t subside when the threat is gone can contribute to everything from autoimmune conditions to cancer.
60 year old and just started IF a week ago. I eat from noon to 8pm. The noon start works for me because I’m not starting my day with the thought of food! I LOVE FOOD AND LOVE TO EAT! I am moving away from some bad habits and it doesn’t seem that difficult for me with IF! Just one week in and I do feel better. Can’t wait till I’ve got a month under my belt.
Understanding the potential adverse effects of intermittent fasting is limited by an inadequate number of rigorous clinical trials. One 2015 review of preliminary clinical studies found that short-term intermittent fasting may produce minor adverse effects, such as continuous feelings of weakness and hunger, headaches, fainting, or dehydration.[29] Long-term, periodic fasting may cause eating disorders or malnutrition, with increased susceptibility to infectious diseases.[29]
After that timespan, your body goes into what is known as the post–absorptive state, which is just a fancy way of saying that your body isn’t processing a meal. The post–absorptive state lasts until 8 to 12 hours after your last meal, which is when you enter the fasted state. It is much easier for you body to burn fat in the fasted state because your insulin levels are low.
Before the Nobel Prize was awarded to Yoshinori Ohsumi, other researchers were making groundbreaking discoveries about autophagy. In 2009, an article was published in Cell Metabolism entitled Autophagy Is Required to Maintain Muscle Mass. In this article, researchers described how deactivating an important autophagy gene resulted in a profound loss in muscle mass and strength.
I’m 63 years old and I have been following a daily 19 hour protocol called Fast 5, fast5.org for two years. I eat lunch at 3pm and dinner at 7pm close my eating window at 8pm. I’ve lost 43 lbs and kept it off, feel great and I am no longer pre diabetic. I eat what I want and don’t track anything. I belong to a Facebook Intermittent fasting group called Fast Club and would to have you check it out. Fasting is free and it works!
Jeremiah, I don’t think the author is suggesting that TRF in the later hours of the day is bad, but rather that it is DIFFICULT. The key finding in this study is that the 07:00-15:00 eaters had a reduced appetite (in other words, didn’t find it very hard to follow this regimen), whereas other approaches have been found to be kind of difficult for some.
Zero-calorie beverages are okay.  I drink green tea in the morning for my caffeine kick while writing. If you want to drink water, black coffee, or tea during your fasted period, that’s okay.  Remember, don’t overthink it – keep things simple! Dr. Rhonda Patrick over at FoundMyFitness believes that a fast should stop at the first consumption of anything other than water, so experiment yourself and see how your body responds.
×