Before the Nobel Prize was awarded to Yoshinori Ohsumi, other researchers were making groundbreaking discoveries about autophagy. In 2009, an article was published in Cell Metabolism entitled Autophagy Is Required to Maintain Muscle Mass. In this article, researchers described how deactivating an important autophagy gene resulted in a profound loss in muscle mass and strength.
So how long does it take to go into ketosis when fasting? On a standard keto diet, it typically takes around 2–3 days to reach ketosis, although it can take up to seven days in some cases. However, many people find that keto adaptation intermittent fasting can speed up the process and help your body burn through glycogen stores more quickly to help enter ketosis.
Not only that, but growth hormone is increased during fasted states (both during sleep [5]and after a period of fasting). Combine this  increased growth hormone secretion:[6], the decrease in insulin production (and thus increase in insulin sensitivity [7]), and you’re essentially priming your body for muscle growth and fat loss with intermittent fasting.
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