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Other studies have found that fasting was as effective as chemotherapeutic agents in delaying progression of different tumors and increased the effectiveness of chemotherapeutic drugs against melanoma, glioma, and breast cancer cells. Although this research may not apply to your life, it does suggest that intermittent fasting can help support your body in times of toxic stress.
Once you start your IF journey, you’ll most likely find that you feel fuller longer and can keep the meals you do eat very simple. There are a few different ways you can fast, so I broke up each of the different plans below into beginner, intermediate, and advanced along with a typical meal plan for each day. The combination of nutrients will give you the energy you need to enhance the benefits of your fasting journey. Just make sure to take into account any individual food intolerances, and use this as a guide for your particular health case, and adjust from there.
This process can be used as a way to get you into ketosis more quickly, so you can transition gracefully into a ketogenic lifestyle or as a way to stimulate autophagy and fat loss. If you can’t go without fat for the full 3 day fast — it’s okay — you will still illicit many of the benefits of fasting by limiting your protein and carbohydrate intake.
Keep these studies in mind as your body tries to play tricks on you during your first day of fasting.  Even after three days of fasting, health complications are highly unlikely. However, it is important to know about the possible issues that can be caused by fasting. If you choose to incorporate fasting into your daily diet, you typically want to eat every day as well. Occasionally going on a longer period of fasting.
Autophagy is spring cleaning for your cells. It’s Latin for “self-eating,” which is spot-on: when autophagy turns on, your cells sift through their internal parts, get rid of anything that’s damaged or old, and install shiny new versions.[8] Autophagy is like a tune-up for your car: afterward everything runs more smoothly. It reduces inflammation and even boosts longevity. Intermittent fasting triggers, to quote researchers, “profound” autophagy, especially in your brain.[9]
Harvard-trained physician and author of The Paleovedic Diet, Dr. Akil Palanisamy further explains to POPSUGAR that "autophagy is the self-cleaning process by which the body's cells break down and recycle damaged proteins and components. This is activated by intermittent fasting, but anything other than water (even black coffee) disrupts it to some extent."

Jerimiah, the linked study in the article (https://www.sciencedirect.com/science/article/pii/S1550413118302535) specifically studied “eTRF”(Early Time-Restricted Feeding) from 8am – 2pm, and implies that eating earlier is better than later. I haven’t read the study (it’s behind a damn Elsevier pay-wall), so I don’t know how strongly they feel about early vs late, though. For me, personally, 12-8 is doable, and skipping dinner (given the existence of a family and the desire to have dinner with said family) isn’t doable, so I’m pleased to hear from you and April above that it’s working. Just starting!
Even though you are skipping breakfast, it's still important to stay hydrated. Make sure to still drink enough water. You can also have herbal tea. The catechins in tea have been shown to enhance the benefits of fasting by helping to further decrease the hunger hormone ghrelin, so you can make it until lunch and not feel deprived. Since you’ve increased your fasting period an extra four hours, you need to make sure your first meal (at noon) has enough healthy fats. The burger in the 8-to-6 window plan will work well, and you can add more fats in with your dressing or top with an avocado!
The benefits of intermittent fasting translate to untrained overweight and obese individuals as well. One study published in Obesity Reviews found that eating fewer calories is effective for fat loss, but it does come with some muscle loss. However, if the subjects fasted for 24 hours and ate as much as they wanted on the next day for a period of 12 weeks, they lost significantly less muscle mass.

So very interesting, I was captivated reading your results—thank you! I would also love to see added to this research the keto effect of just water over those 120 minutes, and then the keto effect of adding collagen powder to your coffee. So appreciative of all that wincing-sticking-your-fingers that you both endured to help give us clarity in what goes on with our ketones and glucose when drinking our coffees with different add-ins. Great read!
So, the idea that intermittent fasting is bad for women is only partially true. Your body will do strange things if it thinks it’s starving. That’s normal, expected, and part of your evolutionary biology. The key to making it work is to give your brain the energy it needs and assuring your metabolism that everything is a-o-k and you’re not in the middle of a famine or disaster.
One potential disadvantage of this schedule is that because you typically cut out a meal or two out of your day, it becomes more difficult to get the same number of calories in during the week. Put simply, it's tough to teach yourself to eat bigger meals on a consistent basis. The result is that many people who try this style of intermittent fasting end up losing weight. That can be a good thing or a bad thing, depending on your goals.
So if both musicians and adamantium-clawed superheroes do Intermittent Fasting, it can probably work for you too, if you can make it work for your particular lifestyle and situation! If you’ve tried implementing something like this in the past and not had success, or you’re just looking for guidance from a coach to help you implement it into your lifestyle, I hear ya!
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