Weight-loss resistance can often be due to an underlying hormone imbalance. Leptin resistance occurs when your brain stops recognizing leptin's signals to use your body’s fat stores for energy. This causes your body to continually store fat instead of using it. Intermittent fasting has been shown to improve chronic inflammation that can dull the brain’s leptin receptor sites.

Conversely, a 2013 study completed by researchers at Washington University School of Medicine, presented the exact opposite, showing increased reactions in receptors on the tongue, when participants were given artificial sweeteners. Their study concluded that if the receptors are capable of detecting sweetness, even though calories aren’t present, a hormonal response (insulin release) is likely.
What and when you eat during the feeding window also depends on when you work out. On days you exercise, carbs are more important than fat. On rest days, fat intake should be higher. Protein consumption should be fairly high every day, though it will vary based on goals, gender, age, body fat and activity levels. Regardless of your specific program, whole, unprocessed foods should make up the majority of your calorie intake. However, when there isn’t time for a meal, a protein shake or meal replacement bar is acceptable (in moderation).

Eat one large meal per day, cutting out all other meals and snacks. For those who aren’t interested in checking clocks and calendars, this is probably the easiest option. This is also a good choice for busy individuals who have a lot going on during the day. Just skip breakfast and lunch and have a large dinner that will carry you over through until bedtime.


Intermittent fasting, commonly referred to as IF, has become all the rage lately, and it doesn't look like the trend is going away anytime soon. The practice of intermittent fasting, or time-restricted feeding, is when a person limits the period of time in which they consume calories down to a limited number of hours. So for example, I practice IF with an eight-hour eating window, which means that I will only eat between the hours of 12 p.m. and 8 p.m.
Conversely, a 2013 study completed by researchers at Washington University School of Medicine, presented the exact opposite, showing increased reactions in receptors on the tongue, when participants were given artificial sweeteners. Their study concluded that if the receptors are capable of detecting sweetness, even though calories aren’t present, a hormonal response (insulin release) is likely.
Yes, by cutting out an entire meal each day, you are consuming fewer calories per week – even if your two meals per day are slightly bigger than before. Overall, you’re still consuming fewer calories per day. This is highlighted in a recent JAMA study[b] in which both calorie restricted dieters and intermittent fasters lost similar amounts of weight over a year period.
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