Those studies above, in working with small sample sizes, and different types of fasting than recommended here, would lead me to believe that fasting affects men and women differently, and that many of the weight loss benefits associated with intermittent fasting (that affect insulin and glucose responses) work positively for men and negatively for women.
Well, most notably, it’s a great way to get lean without going on a crazy diet or cutting your calories down to nothing. In fact, most of the time you'll try to keep your calories the same when you start intermittent fasting. (Most people eat bigger meals during a shorter time frame.) Additionally, intermittent fasting is a good way to keep muscle mass on while getting lean.
You drink sugary beverages, digest them quickly and store the leftovers as body fat. After the initial spike in blood sugar, you experience a dramatic drop, which prompts you to eat more, and what happens? You store more fat. Because of this, it's best to avoid sugary drinks, like soda, lemonade, fruit juices, sweetened iced tea and even some kombucha, completely, whether you're fasting or not.

Although there's no specific dietary recommendation when intermittent fasting, many people choose to combine it with a low-carb, ketogenic diet. When it's time to eat, include foods that are high in good fats and low in carbohydrates. That means eating nuts, seeds, vegetables, avocado, olives, meat and fish, while avoiding whole grains, fruits, starchy vegetables, sugary drinks and anything processed.

One thing to consider about bone broth that sets it apart from plant foods: Even if you do eat a variety of plants that contain collagen-boosting nutrients, if you have a weakened digestive system, you may not fully absorb them. On the other hand, the collagen in bone broth is incredibly easy to absorb, even for those with compromised digestive systems.
To make “down” days easier to stick to, Johnson recommends opting for meal replacement shakes. They’re fortified with essential nutrients and you can sip them throughout the day rather than split into small meals. However, meal replacement shakes should only be used during the first two weeks of the diet — after that, you should start eating real food on “down” days. The next day, eat like normal. Rinse and repeat! (Note: If working out is part of your routine, you may find it harder to hit the gym on the lower calorie days. It may be smart to keep any workouts on these days on the tamer side, or save sweat sessions for your normal calorie days.)
This is excellent, thank you! One thing I would love to see added to this research is the keto effect of just water over those 120 minutes, and THEN the keto effect of adding a tad bit of protein, such as collagen powder (I use the green tub great lakes powder; it dissolves great in coffee). I feel like that might put your test even more into an annals of science, and for us folks who don’t have the finger prick blood testers, it would be fun to know. Also, sugar free sweeteners like splenda (!!) or stevia–do they have any effect? Anyway–great read, exactly what I was looking for when I googled my question.
Fill your plate with plenty of healthy fats, such as coconut oil, avocados, olive oil, ghee and grass-fed butter as well as moderate amounts of protein foods like grass-fed meat, free-range poultry, fatty fish and eggs. Non-starchy vegetables, fresh herbs, nuts, seeds and healthy beverages like water, bone broth and green tea can all be enjoyed as well.
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Keep these studies in mind as your body tries to play tricks on you during your first day of fasting.  Even after three days of fasting, health complications are highly unlikely. However, it is important to know about the possible issues that can be caused by fasting. If you choose to incorporate fasting into your daily diet, you typically want to eat every day as well. Occasionally going on a longer period of fasting.
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What and when you eat during the feeding window also depends on when you work out. On days you exercise, carbs are more important than fat. On rest days, fat intake should be higher. Protein consumption should be fairly high every day, though it will vary based on goals, gender, age, body fat and activity levels. Regardless of your specific program, whole, unprocessed foods should make up the majority of your calorie intake. However, when there isn’t time for a meal, a protein shake or meal replacement bar is acceptable (in moderation).

This is a new area, but the research that has come out since this article is also positive, and promising. One example: In this June 2018 study of 23 people with obesity, 12 weeks of 8-hour time-restricted feeding resulted a 2.6% decrease in body weight and a 7 point decrease in systolic blood pressure, which was significant when compared to controls: https://www.ncbi.nlm.nih.gov/pubmed/29951594
Cons: On the flip side, if you have a hard time handling cheat days the healthy way, this method might not be for you. Additionally, because the plan is pretty specific and the fasting/feeding schedule varies from day to day, this method can be a bit confusing to follow. (However, the plan does come with a calendar, noting how to fast and exercise each day, which may make it easier.)
For this reason, certain experts believe that intermittent fasting improves a broad range of neuro-degenerative conditions, including stroke, Huntington’s disease, Parkinson’s disease, and Alzheimer’s disease. After conducting a study on animals, researchers at the National Institute on Aging, found that cyclical fasting helps neurons in the brain to resist degeneration and dysfunction.
So, the idea that intermittent fasting is bad for women is only partially true. Your body will do strange things if it thinks it’s starving. That’s normal, expected, and part of your evolutionary biology. The key to making it work is to give your brain the energy it needs and assuring your metabolism that everything is a-o-k and you’re not in the middle of a famine or disaster.
With all of these drawbacks, you may be wondering: could you (and would you still want to) practice intermittent fasting as a female? If you take a more relaxed approach, the answer is yes. When done within a briefer timeframe, intermittent fasting may still help you reach your weight loss goals and provide the other benefits previously mentioned, without messing up your hormones.

There is a reason that you crave fatty and salty foods when you’re stressed – adrenal exhaustion. Listening to your body, then eating something soaked in grass-fed butter and coated with high-quality salt gives your adrenal glands what they need. Higher overall fat intake combined with a sprinkle of pink Himalayan salt can do wonders for adrenal function.
Reheating coffee breaks down the components, resulting in a bitter taste. With no cream or sugar to balance the flavoring, black coffee will more immediately taste bitter when reheated. If you find you must reheat your black coffee, absolutely do not use the microwave. Reheating coffee this way will break down the aromas and cause your coffee to taste stale instantly.
Now that you’re properly prepared, it’s time to get started with intermittent fasting keto. In addition to cutting carbs, increasing fat intake and restricting food consumption to a specific window of time each day, you should also be sure to stay hydrated and plan your workout routine around your fasting schedule. While exercising is okay during days that you fast, it’s important to listen to your body and avoid pushing yourself too hard.
This fasting process will not only activate autophagy in your cells, it will also increase your ketones much more quickly than if you were just eating a standard ketogenic diet. If you start implementing intermittent fasting and activities (like walking, cycling, or lifting weights) together, you can raise ketone levels and increase autophagy more than you would with intermittent fasting alone. This suggests that intermittent fasting would be a great addition to your life, but it is important to be familiar with the negative symptoms that can arise before you start.
Two ground-breaking studies have recently been published on the effects of intermittent fasting on males. One group of researchers studied the effects that 16 hours of intermittent fasting had on males that lift weights. They found that muscle mass stayed the same, fat mass decreased significantly, and the males who fasted for 16 hours a day burned more fat for fuel compared to the control group that only fasted for 12 hours.
Crescendo fasting only requires you to fast a few days a week instead of every day. My experience is that women get a lot more benefit from doing it this way without accidentally throwing their hormones into frenzy. This is a more gentle approach that helps the body more easily adapt to fasting. And if women do it right, it can be an amazing way to shave off body fat, improve inflammatory markers and gain energy. (7)
So does that mean you should abstain from your caffeine fix when fasting? According to Dr. Josh Axe, D.N.M., C.N.S., D.C., founder of DrAxe.com, bestselling author of Eat Dirt, and cofounder of Ancient Nutrition, tea and coffee are fine to consume as long as you don't add any milk or sweeteners. He explains on his blog, "If you're on a time-restricted fast and you're in no-eating hours, it's best to stick to no- or low-calorie drinks like water, coffee, (with no milk) and tea. If you're on an alternate day diet or something similar, even during low calorie hours, you can technically drink whatever you'd like — but remember, this will count against your calories." Dr. Palanisamy also agrees that during fasting, the "appetite-suppressing effects of coffee are probably beneficial."
Another program called the 5:2 Fast Diet involves eating 5 days a week and fasting for the other 2 days, when women can get no more than 500 calories and men no more than 600. That’s a quarter of the amount you likely eat on the days when you don’t fast. Whether you eat those calories in one sitting or spread them across micro-meals throughout the day is up to you.
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