Harvard-trained physician and author of The Paleovedic Diet, Dr. Akil Palanisamy further explains to POPSUGAR that "autophagy is the self-cleaning process by which the body's cells break down and recycle damaged proteins and components. This is activated by intermittent fasting, but anything other than water (even black coffee) disrupts it to some extent."
Intermittent fasting isn't a regimen built around limiting calories (although it's likely that your calorie intake will be restricted naturally since you're going a period of time without eating), but it can promote weight loss in a big way. Fasting gives your metabolism an overhaul. It works on the same principles as a ketogenic diet. By restricting food (and carbohydrates), you'll switch your body from burning glucose for energy to burning stored body fat.
^ Jump up to: a b c Harris, L; Hamilton, S; Azevedo, LB; Olajide, J; De Brún, C; Waller, G; Whittaker, V; Sharp, T; Lean, M; Hankey, C; Ells, L (February 2018). "Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis". JBI Database of Systematic Reviews and Implementation Reports. 16 (2): 507–547. doi:10.11124/JBISRIR-2016-003248. PMID 29419624.
There were [no statistical] differences between the low- and high- [meal frequency] groups for adiposity indices, appetite measurements or gut peptides (peptide YY and ghrelin) either before or after the intervention. We conclude that increasing meal frequency does not promote greater body weight loss under the conditions described in the present study.