This is excellent, thank you! One thing I would love to see added to this research is the keto effect of just water over those 120 minutes, and THEN the keto effect of adding a tad bit of protein, such as collagen powder (I use the green tub great lakes powder; it dissolves great in coffee). I feel like that might put your test even more into an annals of science, and for us folks who don’t have the finger prick blood testers, it would be fun to know. Also, sugar free sweeteners like splenda (!!) or stevia–do they have any effect? Anyway–great read, exactly what I was looking for when I googled my question.
Black coffee won't break your fast or take you out of ketosis. In fact, according to a report published in the Journal of Basic and Clinical Physiology and Pharmacology in 2017, caffeine may even increase your metabolism, which will help promote weight loss. Black coffee also helps curb your appetite, which can make getting through your morning fast much more manageable.
On this plan you'll eat clean five days of the week but will not eat anything for two nonconsecutive days of the week. For example, you can fast on Monday and Thursday but eat clean meals on the other days. Food on these five days will look just like the rest of the fasting plans—healthy fats, clean meat sources, vegetables, and some fruit. Keep in mind that this plan is not for beginners, and you should always talk to your doctor before starting any fasting regimen, especially if you are on medication or have a medical condition.
So very interesting, I was captivated reading your results—thank you! I would also love to see added to this research the keto effect of just water over those 120 minutes, and then the keto effect of adding collagen powder to your coffee. So appreciative of all that wincing-sticking-your-fingers that you both endured to help give us clarity in what goes on with our ketones and glucose when drinking our coffees with different add-ins. Great read!
Weight-loss resistance can often be due to an underlying hormone imbalance. Leptin resistance occurs when your brain stops recognizing leptin's signals to use your body’s fat stores for energy. This causes your body to continually store fat instead of using it. Intermittent fasting has been shown to improve chronic inflammation that can dull the brain’s leptin receptor sites.
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
As a functional medicine practitioner, I see a wide range of health problems that all stem from chronic inflammation. And while acute inflammation is a natural and healthy response to help fight off pathogenic bacteria and infections, long-term chronic inflammation that doesn’t subside when the threat is gone can contribute to everything from autoimmune conditions to cancer.

If you're worried you’ll be starving while fasting, you’ll be pleasantly surprised! Intermittent fasting decreases your hunger hormone ghrelin, which in turn can increase dopamine levels in the brain. (Just another example of the gut-brain axis at work.) Fasting can also help free people from emotional eating and kill cravings by transitioning your metabolism from unstable sugar-burning to steady fat-burning.


Second, fasting seems foreign to many of us simply because nobody talks about it that much. The reason for this is that nobody stands to make much money by telling you to not eat their products, not take their supplements, or not buy their goods. In other words, fasting isn't a very marketable topic and so you're not exposed to advertising and marketing on it very often. The result is that it seems somewhat extreme or strange, even though its really not.
Intermittent fasting isn't a regimen built around limiting calories (although it's likely that your calorie intake will be restricted naturally since you're going a period of time without eating), but it can promote weight loss in a big way. Fasting gives your metabolism an overhaul. It works on the same principles as a ketogenic diet. By restricting food (and carbohydrates), you'll switch your body from burning glucose for energy to burning stored body fat.

Intermittent fasting is a technique that involves restricting your food intake to a certain time window each day and then fasting for a specific period. There are several different fasting methods, with many variations that can fit nearly any personal preference or routine. A few of the most common types of intermittent fasting include alternate day fasting, 16/8 fasting and the 5:2 diet, each of which varies based on the amount of time you spend fasting during the week.


Stable blood sugar levels are vital to the success of any diet. This is because when glucose levels plummet, it leads to intense hunger, which almost always results in binge eating. Stable blood sugar levels help eliminate headaches, lack of focus, poor memory, and brain fog as well. Interestingly, these are common complaints among those who follow high carbohydrate diets, as opposed to diets that are rich in fat and protein.
Fast for 16 hours of the day, and allow yourself a single eight-hour window for eating. This may be a good option for most beginners, because it represents the most subtle change from the standard three-meals-per-day lifestyle. As approximately eight of those fasting hours should be spent getting a good night’s sleep, that leaves only eight hours where participants need to be consciously avoiding food. For many, allowing themselves to eat normally from noon until 8pm gives them a stable meal schedule while also staying in a fasted state for the majority of the time.

This fasting process will not only activate autophagy in your cells, it will also increase your ketones much more quickly than if you were just eating a standard ketogenic diet. If you start implementing intermittent fasting and activities (like walking, cycling, or lifting weights) together, you can raise ketone levels and increase autophagy more than you would with intermittent fasting alone. This suggests that intermittent fasting would be a great addition to your life, but it is important to be familiar with the negative symptoms that can arise before you start.
Hello Maria, I can honestly say I look forward to my morning black coffee now, just as much as I enjoy a cup with a little cream, once my eating window opens late afternoon. My easiest “go-to” tip is adding just the smallest pinch of pink Himalayan salt to my coffee. It really works to smooth out the black coffee bitterness! Good luck with your IF journey, Maria!
So how long does it take to go into ketosis when fasting? On a standard keto diet, it typically takes around 2–3 days to reach ketosis, although it can take up to seven days in some cases. However, many people find that keto adaptation intermittent fasting can speed up the process and help your body burn through glycogen stores more quickly to help enter ketosis.

So, if your goal is ketosis, intermittent fasting can help you get into ketosis even faster. Simultaneously, the keto diet makes intermittent fasting more doable because your body is already adapted to fasting with ketones. In addition, most people naturally eat less frequently on keto because of the high satiety level, so you’re likely already used to bigger windows without food.
When the female body senses it’s headed towards famine, it will increase the production of the hunger hormones, ghrelin and leptin, which signal the body that you’re hungry and need to eat (2). Additionally, if there’s not enough food for you to survive, your body is going to shut down the system that would allow you to create another human. This is the body’s natural way of protecting a potential pregnancy, even if you’re not actually pregnant or trying to conceive.
Yes — you read that correctly — 24 hours of intermittent fasting without any resistance training and these subjects were able to preserve more muscle mass than the subjects that ate fewer calories every day without fasting at all. This finding contradicts our common sense, but when we dig deeper into autophagy we can find the mechanism behind this result.
Since all of your hormones are so deeply interconnected, when one hormone is thrown off balance, the rest are also negatively impacted. It’s like a domino effect. As the “messengers” that regulate nearly every function in your body — from energy production to digestion, metabolism, and blood pressure — you don’t want to disrupt their natural rhythm.
You drink sugary beverages, digest them quickly and store the leftovers as body fat. After the initial spike in blood sugar, you experience a dramatic drop, which prompts you to eat more, and what happens? You store more fat. Because of this, it's best to avoid sugary drinks, like soda, lemonade, fruit juices, sweetened iced tea and even some kombucha, completely, whether you're fasting or not.

Expect funny looks if you spend a lot of mornings with breakfast eaters.  A few weeks back I had a number of friends staying with me, and they were all completely dumbfounded when I told them I didn’t eat breakfast anymore. I tried to explain it to them but received a bunch of blank stares. Breakfast has become so enGRAINed (zing!) in our culture that NOT eating it sounds crazy.  You will get weird looks from those around you…embrace it. I still go to brunch or sit with friends, I just drink black coffee and enjoy conversation.
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