As a functional medicine practitioner, I see a wide range of health problems that all stem from chronic inflammation. And while acute inflammation is a natural and healthy response to help fight off pathogenic bacteria and infections, long-term chronic inflammation that doesn’t subside when the threat is gone can contribute to everything from autoimmune conditions to cancer.

Finally, note that fasting to induce ketosis can also trigger a set of symptoms often known as the “keto flu.” Fasting ketosis symptoms may include decreased energy levels, increased cravings, digestive issues, muscle aches and dizziness. These symptoms can last between a few days to a few weeks when starting the ketogenic diet, but they typically subside once your body enters ketosis and begins to adapt.


Intermittent fasting (intermittent energy restriction or intermittent calorie restriction) is an umbrella term for various eating diet plans that cycle between a period of fasting and non-fasting over a defined period. Intermittent fasting is under preliminary research to assess if it can produce weight loss comparable to long-term calorie restriction.[1][2][3][4][5]

Weight-loss resistance can often be due to an underlying hormone imbalance. Leptin resistance occurs when your brain stops recognizing leptin's signals to use your body’s fat stores for energy. This causes your body to continually store fat instead of using it. Intermittent fasting has been shown to improve chronic inflammation that can dull the brain’s leptin receptor sites.
Intermittent fasting and the ketogenic diet are two of the top trending eating patterns among dieters and health enthusiasts alike. However, while there are plenty of differences between intermittent fasting vs. keto, they can actually be combined to help amplify results and reach ketosis even faster. In fact, by practicing intermittent fasting on keto, you can take advantage of the unique benefits that both have to offer.
I believe this is a disservice to those, like me, with a history of eating disorder. It has made experimenting with IF unnecessarily stressful. Despite my worry about what might happen (reading all these baseless cautions), I went ahead and experimented. In my experience, contrary to this “expert advice”, IF has been the most profoundly effective intervention I’ve experienced for my bulemia.
Jerimiah, the linked study in the article (https://www.sciencedirect.com/science/article/pii/S1550413118302535) specifically studied “eTRF”(Early Time-Restricted Feeding) from 8am – 2pm, and implies that eating earlier is better than later. I haven’t read the study (it’s behind a damn Elsevier pay-wall), so I don’t know how strongly they feel about early vs late, though. For me, personally, 12-8 is doable, and skipping dinner (given the existence of a family and the desire to have dinner with said family) isn’t doable, so I’m pleased to hear from you and April above that it’s working. Just starting!
So, what exactly is a relaxed approach to intermittent fasting? Again, since there’s little research done on intermittent fasting, we’re dealing with a bit of a gray area. The opinions also tend to vary depending on which site you visit, or which health expert you ask. From what we’ve found, the general guidelines to brief intermittent fasting for women are:
Does adding cream to your coffee make you hungrier throughout the rest of your fast? If yes, then you know you have spiked an insulin response and cream is a no-go for you! Hunger and cravings initially are common, but after a few days of routine fasting, if these symptoms continue, it is an indication that something is triggering an insulin response in you, causing these cravings. Is it something you’re adding to your coffee?
IF makes intuitive sense. The food we eat is broken down by enzymes in our gut and eventually ends up as molecules in our bloodstream. Carbohydrates, particularly sugars and refined grains (think white flours and rice), are quickly broken down into sugar, which our cells use for energy. If our cells don’t use it all, we store it in our fat cells as, well, fat. But sugar can only enter our cells with insulin, a hormone made in the pancreas. Insulin brings sugar into the fat cells and keeps it there.
How It Works: Warriors-in-training can expect to fast for about 20 hours every day and eat one large meal every night. What you eat and when you eat it within that large meal is also key to this method. The philosophy here is based on feeding the body the nutrients it needs in sync with circadian rhythms and that our species are “nocturnal eaters, inherently programmed for night eating.”
Yes — you read that correctly — 24 hours of intermittent fasting without any resistance training and these subjects were able to preserve more muscle mass than the subjects that ate fewer calories every day without fasting at all. This finding contradicts our common sense, but when we dig deeper into autophagy we can find the mechanism behind this result.
Some people believe that IF has worked for them simply because the limited eating window naturally helps them reduce the amount of calories they consume. For instance, instead of eating three meals and two snacks, they might find that they only have time for two meals and one snack. They become more mindful about the kinds of food they consume and tend to stay way from processed carbs, unhealthy fat, and empty calories.
That’s what I suggest you do when you start fasting. It should happen naturally, and you shouldn’t have to force it. If you’re still a sugar burner instead of a fat burner, it’s going to be much harder…so if you’re serious about trying out this whole fasting thing, I suggest slowly transitioning to a high-fat low-carb diet. You can read about the benefits here.
When the female body senses it’s headed towards famine, it will increase the production of the hunger hormones, ghrelin and leptin, which signal the body that you’re hungry and need to eat (2). Additionally, if there’s not enough food for you to survive, your body is going to shut down the system that would allow you to create another human. This is the body’s natural way of protecting a potential pregnancy, even if you’re not actually pregnant or trying to conceive.
Surprisingly, since I've started intermittent fasting I've increased muscle mass (up 10 pounds from 205 to 215), decreased body fat (down 3% from 14% to 11%), increased explosiveness (set a personal best with a clean and jerk of 253 pounds a few months back), and decreased the amount of time I've spent training (down from 7.5 hours per week to 2.5 hours per week).

Many people achieve the best results by starting the ketogenic diet first and then beginning intermittent fasting several weeks later. Although this is a bit different from the classic approach to the keto-intermittent fasting diet, it works better for some individuals. This is because intermittent fasting, as previously mentioned, should be a natural process, during which you should not feel deprived and hungry.
Cons: On the flip side, if you have a hard time handling cheat days the healthy way, this method might not be for you. Additionally, because the plan is pretty specific and the fasting/feeding schedule varies from day to day, this method can be a bit confusing to follow. (However, the plan does come with a calendar, noting how to fast and exercise each day, which may make it easier.)

After determining your preferred protocol of intermittent fasting, you should start planning out your diet for the days that you do eat. On a standard keto diet, 75 percent of total calories should come from fat, 20 percent should be from protein and 5 percent should come from carbs. When getting started, however, you can start with a modified keto diet instead, which is often considered more flexible and easy-to-follow. With this diet plan, about 40–60 percent of calories should come from healthy keto fats with 20–30 percent from protein foods and 15–25 percent from carbohydrates.
Following what Greg lays out for us, we should wait a couple of hours and stave off our cup of jolt, kick-starter for at least a couple of hours after getting up. Instead, we should have some hydrating water. That’s a hard one, let’s be truthful. Real hard, especially for coffee lovers, but I suppose there is a reason for this. I think this has something to do with cortisol levels. This really helps when, or if you get hunger pains and then have a cup of wakey juice or two or three or four cups. This almost always alleviates the hunger, so this is why it’s so powerful.

I was very curious about this, so I asked the opinion of metabolic expert Dr. Deborah Wexler, Director of the Massachusetts General Hospital Diabetes Center and associate professor at Harvard Medical School. Here is what she told me. “There is evidence to suggest that the circadian rhythm fasting approach, where meals are restricted to an eight to 10-hour period of the daytime, is effective,” she confirmed, though generally she recommends that people “use an eating approach that works for them and is sustainable to them.”
Since all of your hormones are so deeply interconnected, when one hormone is thrown off balance, the rest are also negatively impacted. It’s like a domino effect. As the “messengers” that regulate nearly every function in your body — from energy production to digestion, metabolism, and blood pressure — you don’t want to disrupt their natural rhythm.
When you eat a meal, your body spends a few hours processing that food, burning what it can from what you just consumed.  Because it has all of this readily-available, easy to burn energy (thanks to the food you ate), your body will choose to use that as energy rather than the fat you have stored.  This is especially true if you just consumed carbohydrates/sugar, as your body prefers to burn sugar as energy before any other source.
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